Company Profile

IOTA NanoSolutions Limited is a nanomaterials engineering company specialising in the delivery and formulation of poorly soluble ingredients. In so doing IOTA NanoSolutions’ technologies can help overcome many of the factors that prevent the use and full value-realisation of many poorly soluble actives. IOTA NanoSolutions has actively developed a number of novel generic approaches to enable the formation of dry physical blends of insoluble and soluble materials. The blends are produced without a traditional particle formation step such as milling and are equally applicable with amorphous, crystalline or waxy materials. When the blends are added to a liquid the soluble material dissolves consequently releasing the insoluble material as a nanodispersion.

Materials processed by IOTA NanoSolutions can be used to form nanodispersions in almost any liquid ranging from water to natural fluids, hydrophilic/hydrophobic solvents, monomers or oils. The nanodispersions are often transparent although nanoparticles of the insoluble material can be present at concentrations unobtainable through traditional techniques.

IOTA NanoSolutions’ technologies offer a range of significant benefits

• Insoluble materials stored as ‘nano-concentrates’ in stable solid formats
• Rapid nanodispersion formation
• No chemical modification of active ingredients
• Wide applicability to insoluble & poorly soluble materials
• Applicable to low melting point/thermally sensitive actives
• Large scale production without use of novel manufacturing equipment

Benefits of IOTA NanoSolutions’ dispersions and powder ‘nano-concentrates’

• Ease of formulation and use of insoluble materials
• High concentration of insoluble active in chosen media
• Case Study 1: Enhanced Bioactivity
• Removal of need for high concentrations of surfactants or toxic solvents
• Environmentally non-persistent particles
• Tuning/triggering of active release into non-solvents